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「Biophysics and Physicobiology」に Akihiro Sakama, Mariko Orioka, Yuki Hiruta による "Current advances in the development of bioluminescent probes toward spatiotemporal trans-scale imaging" をJ-STAGEの早期公開版として掲載

2024年02月02日 学会誌

日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が早期公開されました。

Akihiro Sakama, Mariko Orioka, Yuki Hiruta
"Current advances in the development of bioluminescent probes toward spatiotemporal trans-scale imaging"

URL:https://doi.org/10.2142/biophysico.bppb-v21.s004


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Abstract
Bioluminescence imaging has recently attracted great attention as a highly sensitive and non-invasive analytical method. However, weak signal and low chemical stability of the luciferin are conventional drawbacks of bioluminescence imaging. In this review article, we describe the recent progress on the development and applications of bioluminescent probes for overcoming the aforementioned limitations, thereby enabling spatiotemporal trans-scale imaging. The detailed molecular design for manipulation of their luminescent properties and functions enabled a variety of applications, including in vivo deep tissue imaging, long-term imaging, and chemical sensor.


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