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「Biophysics and Physicobiology」に Hiroshi Imamura, Yasuhiro Isogai, Tsuyoshi Shirai による "Resurrecting lost ancient myoglobin proteins to elucidate mechanisms of diving adaptation in mammals" をJ-STAGEの早期公開版として掲載

2026年01月16日 学会誌

日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が早期公開されました。

Hiroshi Imamura, Yasuhiro Isogai, Tsuyoshi Shirai
"Resurrecting lost ancient myoglobin proteins to elucidate mechanisms of diving adaptation in mammals"

URL:https://doi.org/10.2142/biophysico.bppb-v23.0004


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Abstract
Data science methodologies can be applied to “molecular archeology.” By statistically inferring ancestral gene or protein sequences from a molecular phylogeny, researchers can recreate ancient molecules for laboratory experiments, allowing direct examination of their properties and structures. This review summarizes studies that applied this approach to investigate how whales and seals readapted to deep-sea diving through the evolutionary modification of myoglobins.

URL: https://doi.org/10.2142/biophysico.bppb-v23.0004


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