Gallery of the Recent Covers
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Volume 22, 2025
Issue 4
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Volume 22, 2025
Issue 3
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Volume 22, 2025
Issue 3
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Volume 22, 2025
Issue 2
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News

04 Aug., 2025 The promotional video for every article in BPPB except those of the category of Commentary and Perspective or Editorial will be released on YouTube as of Issue 3, Volume 22 (2025).
21 May, 2025 As of May 2025, a short caption for the Graphical Abstract is requested for each BPPB paper except the category of Commentary & Perspective or Editorial.
12 May, 2025 As of May 2025, each article published in BPPB may be licensed under either the Creative Commons Attribution (CC BY) 4.0 license or the Creative Commons Attribution-NonCommercial-ShareAlike (CC BY-NC-SA) 4.0 license, depending on the authors’ selection.
01 Jan., 2025 Because of the minor corrections about the manuscript style, the pages of “Instruction for Authors” and "Quick Guide to Prepare Manuscript" for Biophysics and Physicobiology have been slightly updated. The Template files have also been replaced.
14 Nov., 2024 Special Issue: "IUPAB2024 Congress in Kyoto" has been published.
29 Aug., 2024 The article "Editorial: IUPAB2024 Congress in Kyoto" has been published in the Special Issue together with total 1,339 Abstracts of the oral and poster presentations as the Supplementary Materials.
29 May, 2024 Special Issue: "Singularity Biology and Beyond" has been published.
27 May, 2024 Publication of "The Oosawa Lectures on DIY Statistical Mechanics" has been completed as the Special Issue of Biophysics and Physicobiology of Volume 18.
30 Jan., 2024 The “Instruction for Authors” for Biophysics and Physicobiology has been updated. In particular, our policy for the articles prepared with the aid of Large Language Models and/or Generative AI is added.
30 Jun., 2023 2022 Journal Impact Factor of Biophysics and Physicobiology is given as 1.5 by Clarivate.
21 Mar., 2023 Special Issue: "Recent Advances in Retinal Protein Research" has been published.

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Recent Articles

Advance online publication
Physicochemical, functional, and evolutionary characteristics of protein loop regions in human and Escherichia coli proteomes
Lin Zhang, Hafumi Nishi

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0031
ReceivedMay 27, 2024   
AcceptedNovember 20, 2025   
ReleasedNovember 22, 2025   

Advance online publication
Schiff base deprotonation and structural changes in a mouse UV-sensitive cone visual pigment revealed by FTIR spectroscopy at 77 K
Yosuke Mizuno, Sora Arai, Kota Katayama, Hideki Kandori

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0030
ReceivedOctober 09, 2025   
AcceptedNovember 15, 2025   
ReleasedNovember 21, 2025   

Advance online publication
FTIR study of the wild-type and mutant proteins of a viral rhodopsin, OLPVR1
Mako Aoyama, Kota Katayama, Hideki Kandori

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0029
ReceivedOctober 07, 2025   
AcceptedNovember 10, 2025   
ReleasedNovember 12, 2025   

Advance online publication
Selection–diversification interplay in oligonucleotide chemical evolution
Jiro Kakizaki, Ryo Mizuuchi

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0028
ReceivedSeptember 16, 2025   
AcceptedNovember 01, 2025   
ReleasedNovember 05, 2025   

Editorial
Announcement of BPPB paper awards 2025
Haruki Nakamura

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0027
ReceivedOctober 21, 2025   
AcceptedOctober 21, 2025   
ReleasedOctober 23, 2025   

Regular Article
Fractal dimensions for tumour-related cell types of prostate cancer on histopathology images using multiple-threshold box counting algorithm
Anton Schwarz, Hidetaka Arimura, Yunhao Cui, Shun Shimabukuro, Qijing Lin, Yu Jin, Satoshi Kobayashi, Takashi Matsumoto, Masaki Shiota, Masatoshi Eto, Yoshinao Oda

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0026
ReceivedSeptember 04, 2025   
AcceptedOctober 06, 2025   
ReleasedOctober 18, 2025   

Method and Protocol (Invited)
A platform for analyzing translational control by RBPs at single-mRNA resolution in cells
Hotaka Kobayashi, Robert H. Singer

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0025
ReceivedSeptember 01, 2025   
AcceptedOctober 06, 2025   
ReleasedOctober 08, 2025   

Regular Article
Molecular properties of a viral heliorhodopsin, V2HeR2
Ritsu Mizutori, Kota Katayama, Masae Konno, Keiichi Inoue, Oded Béjà, Hideki Kandori

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0024
ReceivedJune 24, 2025   
AcceptedOctober 02, 2025   
ReleasedOctober 04, 2025   

Review Article (Invited)
Stress fiber contraction induces cell body rotation in single keratocytes
Chika Okimura

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0023
ReceivedJuly 25, 2025   
AcceptedOctober 02, 2025   
ReleasedOctober 04, 2025   

Regular Article
Finding differentially expressed genes between cell fates predicted by image-based deep learning
Tomoaki Okaniwa, Kirill Kryukov, Katsuyuki Shiroguchi

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0022
ReceivedMay 02, 2025   
AcceptedSeptember 24, 2025   
ReleasedSeptember 26, 2025   

Commentary and Perspective
Interdisciplinary investigations into the biophysics of the origins of life
Tony Z. Jia, Yutetsu Kuruma

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0021
ReceivedSeptember 08, 2025   
AcceptedSeptember 10, 2025   
ReleasedSeptember 12, 2025   

Commentary and Perspective
Approaching active matter from biophysics perspective
Masayuki Hayakawa, Ibuki Kawamata

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0020
ReceivedAugust 25, 2025   
AcceptedAugust 29, 2025   
ReleasedAugust 30, 2025   

Regular Article
Visualization of peptidoglycan layer isolated from gliding diderm bacteria, Flavobacterium johnsoniae and Myxococcus xanthus, by quick-freeze deep-etch replica electron microscopy
Yuhei O. Tahara, Tâm Mignot, Makoto Miyata

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0019
ReceivedFebruary 06, 2025   
AcceptedAugust 22, 2025   
ReleasedAugust 26, 2025   

Regular Article
Origin of the unique topology of the triangular water cluster in Rubrobacter xylanophilus rhodopsin
Tomoyasu Noji, Msasaki Tsujimura, Keisuke Saito, Keiichi Kojima, Yuki Sudo, Hiroshi Ishikita

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0018
ReceivedApril 28, 2025   
AcceptedAugust 21, 2025   
ReleasedAugust 23, 2025   

Regular Article
Polymerization and stability of actin conjugated with polyethylene glycol
Masaya Sagara, Kuniyuki Hatori

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0017
ReceivedMarch 10, 2025   
AcceptedAugust 06, 2025   
ReleasedAugust 08, 2025   

Regular Article
Characterizing deterioration of milk through bioimpedance spectroscopy
Abhishek Mallick, Bishal Paul, Anirudhha Roy, Arijit Roy

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0016
ReceivedApril 21, 2025   
AcceptedJuly 29, 2025   
ReleasedAugust 02, 2025   

Regular Article
Protein–ligand affinity prediction via Jensen-Shannon divergence of molecular dynamics simulation trajectories
Kodai Igarashi, Masahito Ohue

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0015
ReceivedFebruary 20, 2025   
AcceptedJuly 11, 2025   
ReleasedJuly 16, 2025   

Regular Article
HulaChrimson: A Chrimson-like cation channelrhodopsin discovered using freshwater metatranscriptomics from Lake Hula
Hiroto Takahashi, Shunki Takaramoto, Takashi Nagata, Shai Fainsod, Yoshitaka Kato, Oded B?j?, Keiichi Inoue

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0014
ReceivedApril 14, 2025   
AcceptedJuly 03, 2025   
ReleasedJuly 05, 2025   

Review Article (Invited)
Cytoskeleton as a generator of characteristic physical properties of plant cells: ‘cell wall,’ ‘large vacuole,’ and ‘cytoplasmic streaming’
Amari Toshiki, Noriko Nagata, Motoki Tominaga, Hirotomo Takatsuka

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0013
ReceivedJanuary 31, 2025   
AcceptedJune 18, 2025   
ReleasedJune 20, 2025   

Method and Protocol
A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality
Arima Okutani, Jannatul Naima, Asaka Ogihara, Taihei Motoichi, Ikuroh Ohsawa, Yoshihiro Ohta

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0012
ReceivedApril 07, 2025   
AcceptedMay 14, 2025   
ReleasedMay 16, 2025   

Regular Article
A virtual system-coupled molecular dynamics simulation free from experimental knowledge on binding sites: Application to RNA-ligand binding free-energy landscape
Junichi Higo, Kota Kasahara, Shun Sakuraba, Gert-Jan Bekker, Narutoshi Kamiya, Ikuo Fukuda, Takuya Takahashi, Yoshifumi Fukunishi

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0011
ReceivedJanuary 10, 2025   
AcceptedApril 24, 2025   
ReleasedApril 26, 2025   

Method and Protocol
A low-cost electric micromanipulator and its application to single-cell electroporation
Kazuma Shimizu, Norihiko Nishimura, Manato Oku, Chika Okimura, Yoshiaki Iwadate

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0010
ReceivedNovember 07, 2024   
AcceptedApril 24, 2025   
ReleasedApril 26, 2025   

Regular Article
Structure-activity relationship of PET-degrading cutinase regulated by weak Ca2+ binding and temperature
Fumiya Kondo, Narutoshi Kamiya, Gert-Jan Bekker, Satoshi Nagao, Nobutaka Numoto, Hiroshi Sekiguchi, Nobutoshi Ito, Masayuki Oda

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0009
ReceivedMarch 10, 2025   
AcceptedApril 22, 2025   
ReleasedApril 24, 2025   

Review Article
Genetically-encoded temperature indicators for thermal biology
Tetsuichi Wazawa, Ryohei Ozaki-Noma, Lu Kai, Shun-ichi Fukushima, Tomoki Matsuda, Takeharu Nagai

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0008
ReceivedDecember 14, 2024   
AcceptedApril 03, 2025   
ReleasedApril 08, 2025   

Method and Protocol
Time-resolved small-angle X-ray scattering system development for the biological macromolecules at SACLA: A pilot study
Nobutaka Shimizu, Fangjia Luo, Tomoyuki Tanaka, Kensuke Tono, Keiko Yatabe, So Iwata, Eriko Nango

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0007
ReceivedOctober 23, 2024   
AcceptedMarch 25, 2025   
ReleasedMarch 27, 2025   

Regular Article
Gliding direction of Mycoplasma mobile correlates with the curved configuration of its cell shape
Kana Suzuki, Daisuke Nakane, Masaki Mizutani, Takayuki Nishizaka

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0006
ReceivedJanuary 17, 2025   
AcceptedFebruary 17, 2025   
ReleasedFebruary 26, 2025   

Regular Article
Exploring hydrophilic sequence space to search for uncharted foldable proteins by AlphaFold2
Naoki Tomita, Hiroki Onoda, Leonard M. G. Chavas, George Chikenji

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0005
ReceivedNovember 06, 2024   
AcceptedJanuary 30, 2025   
ReleasedFebruary 01, 2025   

Regular Article
Product release and substrate entry of aldehyde deformylating oxygenase revealed by molecular dynamics simulations
Masataka Yoshimura, Munehito Arai

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0003
ReceivedDecember 16, 2024   
AcceptedDecember 27, 2024   
ReleasedJanuary 09, 2025   

Regular Article
Measurement of protoplasmic streaming over the entire body of Physarum plasmodium, and estimation of the transport and mixing of protoplasma through the intricate vein network
Yo Sato, Charles Fosseprez, Yukinori Nishigami, Katsuhiko Sato, Hiroshi Orihara, Toshiyuki Nakagaki

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0002
ReceivedJuly 17, 2024   
AcceptedDecember 24, 2024   
ReleasedJanuary 09, 2025   

Regular Article
Near-infrared spectroscopic study of blood flow changes in the dorsolateral prefrontal cortex during pain relief by odor stimulation
Yuki Okamura, Shogo Takayama, Kengo Namiki, Fusako Koshikawa, Etsuro Ito

DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0001
ReceivedJuly 26, 2024   
AcceptedDecember 24, 2024   
ReleasedDecember 26, 2024   

Regular Article
Neuron with well-designed ionic system
Takayoshi Tsubo

DOIhttps://doi.org/10.2142/biophysico.bppb-v21.0028
ReceivedOctober 15, 2024   
AcceptedDecember 10, 2024   
ReleasedDecember 13, 2024   

Regular Article
Comparative study of alpha-glucosidase inhibition of four Vietnamese medicinal plants Combretum quadrangulare, Dicranopteris linearis, Psychotria adenophylla, and Garcinia schomburgkiana: In vitro and in vivo studies
Thi-Hong-Tuoi Do, Thuc-Huy Duong, Huu-Hung Nguyen, Thanh-Sang Vo, Ngoc-Hong Nguyen, Huong Thuy Le

DOIhttps://doi.org/10.2142/biophysico.bppb-v21.0027
ReceivedJuly 23, 2024   
AcceptedDecember 09, 2024   
ReleasedDecember 13, 2024   

Commentary and Perspective (Invited)
Half a Century of Biophysics: A Comparison of Presentation Statistics from the 6th and 21st IUPAB Congresses
Mikio Kataoka, Kuniaki Nagayama

DOIhttps://doi.org/10.2142/biophysico.bppb-v21.e2013
ReceivedNovember 20, 2024   
AcceptedDecember 05, 2024   
ReleasedDecember 07, 2024   

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