Biophysics and Physicobiology
Published by the Biophysical Society of Japan
- Editor-in-chief
- : Haruki Nakamura
- Online ISSN
- : 2189-4779
- Journal Impact Factor (2024)
- : 1.6
- DOAJ (The Directory of Open Access Journals) archive for BPPB:
- PMC (PubMed Central) archive for BPPB:
- B2J service at bioRxiv is available
- Either CC BY-NC-SA 4.0 or CC BY 4.0 by the authors’ preference
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News
| 26 Dec., 2025 | Special Issue: "Towards the International Conference on Biophysics and Biomedical Sciences: ICBBS 2026" has been published. |
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| 24 Dec., 2025 | As of December 2025, the Article Statistics page features the total number of PDF downloads and citations for each published article. |
| 19 Dec., 2025 | The “Instructions for Authors” for Biophysics and Physicobiology has been updated, specifically regarding the policies for AI usage by authors and reviewers. |
| 04 Aug., 2025 | The promotional video for every article in BPPB except those of the category of Commentary and Perspective or Editorial will be released on YouTube as of Issue 3, Volume 22 (2025). |
| 21 May, 2025 | As of May 2025, a short caption for the Graphical Abstract is requested for each BPPB paper except the category of Commentary & Perspective or Editorial. |
| 12 May, 2025 | As of May 2025, each article published in BPPB may be licensed under either the Creative Commons Attribution (CC BY) 4.0 license or the Creative Commons Attribution-NonCommercial-ShareAlike (CC BY-NC-SA) 4.0 license, depending on the authors’ selection. |
| 01 Jan., 2025 | Because of the minor corrections about the manuscript style, the pages of “Instruction for Authors” and "Quick Guide to Prepare Manuscript" for Biophysics and Physicobiology have been slightly updated. The Template files have also been replaced. |
| 14 Nov., 2024 | Special Issue: "IUPAB2024 Congress in Kyoto" has been published. |
| 29 Aug., 2024 | The article "Editorial: IUPAB2024 Congress in Kyoto" has been published in the Special Issue together with total 1,339 Abstracts of the oral and poster presentations as the Supplementary Materials. |
| 29 May, 2024 | Special Issue: "Singularity Biology and Beyond" has been published. |
| 27 May, 2024 | Publication of "The Oosawa Lectures on DIY Statistical Mechanics" has been completed as the Special Issue of Biophysics and Physicobiology of Volume 18. |
| 30 Jan., 2024 | The “Instruction for Authors” for Biophysics and Physicobiology has been updated. In particular, our policy for the articles prepared with the aid of Large Language Models and/or Generative AI is added. |
| 30 Jun., 2023 | 2022 Journal Impact Factor of Biophysics and Physicobiology is given as 1.5 by Clarivate. |
| 21 Mar., 2023 | Special Issue: "Recent Advances in Retinal Protein Research" has been published. |
Recent Articles
Advance online publication Revisiting hydrolytic mechanisms of bacterial RNase HI: Towards clarification of single mobile Mg2+ action in nuclease reactions Kosuke Morikawa, Takuji Oyama, Masayuki Oda DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0014 ReceivedMarch 30, 2026 AcceptedApril 14, 2026 ReleasedApril 18, 2026 CitationsStill Uncounted DownloadsStill Uncounted |
Advance online publication Oligo DNA-based quantum dot (QD) single-particle tracking for multicolor single-molecule imaging Shigeo Sakuragi, Naoki Kato, Tomoya Uchida, Boxiao Zhao, Taro Katagiri, Miyu Enomoto, Rie Kato, Hideaki Yoshimura, Chisato Oyama, Iona Katayama, Ayano Chikuma, Yuji Teramura, Hiroko Bannai DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0013 ReceivedOctober 14, 2025 AcceptedMarch 24, 2026 ReleasedMarch 27, 2026 Citations0 Downloads29 |
Advance online publication Cooperative and divergent properties of bacterial actin isoforms in Spiroplasma swimming Daichi Takahashi, Makoto Miyata, Ikuko Fujiwara DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0012 ReceivedJanuary 06, 2026 AcceptedMarch 11, 2026 ReleasedMarch 12, 2026 Citations0 Downloads99 |
Regular Article NMR evidence for residue-based LFER relationship in two-state folding-unfolding equilibrium of the spectrin SH3 domain in acidic solutions Seiichiro Hayashi, Daisuke Fujinami, Daisuke Kohda DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0011 Promotional Videohttps://www.youtube.com/watch?v=znGXcJEGKkM ReceivedDecember 15, 2025 AcceptedFebruary 26, 2026 ReleasedMarch 05, 2026 Citations0 Downloads127 |
Note Liquid-liquid phase separation and its regulation of the BACH2 intrinsically disordered region Hironori Hayashi, Miyuki Kato-Murayama, Takeshi Kurasawa, Eiichi N. Kodama, Mikako Shirouzu, Kazuhiko Igarashi, Kazutaka Murayama DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0010 Promotional Videohttps://www.youtube.com/watch?v=aYxCQldA7Jk ReceivedOctober 24, 2025 AcceptedFebruary 20, 2026 ReleasedFebruary 25, 2026 Citations0 Downloads115 |
Commentary and Perspective The Norway–Japan bilateral symposium: Dialogue in biophysics beginning in Nara Yoshihiko Furuike, Oliver Vanderpoorten DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0009 ReceivedJanuary 16, 2026 AcceptedFebruary 18, 2026 ReleasedFebruary 20, 2026 Citations0 Downloads101 |
Commentary and Perspective Mirror life at the crossroads: Report on the symposia in Japan for discussion toward mirror life synthesis Kei Fujiwara,Wataru Aoki,Chikara Furusawa,Ai Hasegawa,Gosuke Hayashi,Daisuke Kiga,Koichi Mikami,Sakura Takada,Yoshihiro Shimizu DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0008 ReceivedJanuary 06, 2026 AcceptedFebruary 18, 2026 ReleasedFebruary 20, 2026 Citations0 Downloads216 |
Review Article Modeling of viscous frictional force in multicellular morphogenesis Hiroshi Koyama, Yasuhiro Inoue DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0007 Promotional Videohttps://www.youtube.com/watch?v=H0USgSgRY-M ReceivedDecember 05, 2025 AcceptedFebruary 17, 2026 ReleasedFebruary 19, 2026 Citations0 Downloads286 |
Regular Article Comparative evaluation of electrode configuration for optimizing positive dielectrophoresis trapping of CCRF-CEM cells Miftakhul Firdhaus, Ulya Farahdina, Nasori Nasori, Endarko Endarko, Agus Rubiyanto DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0006 Promotional Videohttps://www.youtube.com/watch?v=GBeLwMslAcU ReceivedDecember 08, 2025 AcceptedFebruary 11, 2026 ReleasedFebruary 17, 2026 Citations0 Downloads110 |
Regular Article Mechanistic insights into a cold-adapted glucokinase with high thermal stability were revealed by site-directed spin labeling ESR Akane Yato, Masaki Horitani DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0005 Promotional Videohttps://www.youtube.com/watch?v=sTxNTjA_vUA ReceivedNovember 27, 2025 AcceptedJanuary 22, 2026 ReleasedFebruary 17, 2026 Citations0 Downloads79 |
Review Article (Invited) Resurrecting lost ancient myoglobin proteins to elucidate mechanisms of diving adaptation in mammals Hiroshi Imamura, Yasuhiro Isogai, Tsuyoshi Shirai DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0004 Promotional Videohttps://www.youtube.com/watch?v=WgSN4WEhWks ReceivedDecember 04, 2025 AcceptedJanuary 14, 2026 ReleasedJanuary 16, 2026 Citations0 Downloads268 |
Regular Article Development of electromagnetic tweezers for single-molecule energetics of kinesin Haruyuki Fukuzawa, Yuga Ihara, Masato Sawa, Hidekazu Shirai, Sawako Enoki, Keigo Ikezaki, Taketoshi Kambara, Yasushi Okada DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0003 Promotional Videohttps://www.youtube.com/watch?v=t8_MGoPE1jA ReceivedNovember 04, 2025 AcceptedJanuary 05, 2026 ReleasedJanuary 07, 2026 Citations0 Downloads478 |
Method and Protocol High-sensitivity method for detecting dielectric changes in water driven by biomolecular hydration Masahiko Imashimizu, Jun-ichi Sugiyama DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0002 Promotional Videohttps://www.youtube.com/watch?v=jgYpSijNtrk ReceivedJune 16, 2025 AcceptedDecember 18, 2025 ReleasedDecember 24, 2025 Citations1 Downloads285 |
Regular Article Analysis of metabolic stability under environmental perturbations using a kinetic model Atsuki Hishida, Yusuke Himeoka, Chikara Furusawa DOIhttps://doi.org/10.2142/biophysico.bppb-v23.0001 Promotional Videohttps://www.youtube.com/watch?v=v2FKT8M9fsc ReceivedAugust 25, 2025 AcceptedDecember 08, 2025 ReleasedDecember 24, 2025 Citations0 Downloads359 |
Commentary and Perspective (Invited) From coordination to function: Inorganic insights into metalloproteins and metallopeptides in biosystems Jiyeon Han DOIhttps://doi.org/10.2142/biophysico.bppb-v22.s006 ReceivedDecember 01, 2025 AcceptedDecember 08, 2025 ReleasedDecember 12, 2025 Citations0 Downloads159 |
Commentary and Perspective (Invited) Brief history of international joint symposiums in BSJ Takayuki Nishizaka DOIhttps://doi.org/10.2142/biophysico.bppb-v22.s005 ReceivedDecember 05, 2025 AcceptedDecember 10, 2025 ReleasedDecember 12, 2025 Citations0 Downloads128 |
Commentary and Perspective (Invited) The future of Asian biophysics built through Korea–Japan collaboration Chihong Song DOIhttps://doi.org/10.2142/biophysico.bppb-v22.s004 ReceivedNovember 04, 2025 AcceptedNovember 25, 2025 ReleasedDecember 12, 2025 Citations0 Downloads221 |
Commentary and Perspective (Invited) Japan–Korea collaboration on biophysical techniques for drug discovery in infectious diseases: Toward future pandemic preparedness Katsumi Maenaka DOIhttps://doi.org/10.2142/biophysico.bppb-v22.s003 ReceivedNovember 10, 2025 AcceptedDecember 03, 2025 ReleasedDecember 12, 2025 Citations0 Downloads156 |
Commentary and Perspective (Invited) Korea-Japan Biophysics Collaboration: A journey through microbial rhodopsin research Jae-Hyun Park DOIhttps://doi.org/10.2142/biophysico.bppb-v22.s002 ReceivedOctober 30, 2025 AcceptedNovember 26, 2025 ReleasedDecember 12, 2025 Citations0 Downloads153 |
Regular Article Molecular dynamics simulations of amyloid-β(29–42) aggregation in bulk water and at the air–water interface Anne-Idil Farah, Satoru G. Itoh, Hisashi Okumura DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0033 Promotional Videohttps://www.youtube.com/watch?v=rZoUp417iAw ReceivedOctober 27, 2025 AcceptedDecember 03, 2025 ReleasedDecember 06, 2025 Citations0 Downloads348 |
Regular Article Protonation states of highly conserved carboxylic acids in NeoR Ritsu Mizutori, Masahiro Sugiura, Hideki Kandori DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0032 Promotional Videohttps://www.youtube.com/watch?v=Zq9WrSmYVCU ReceivedNovember 13, 2025 AcceptedDecember 02, 2025 ReleasedDecember 06, 2025 Citations0 Downloads476 |
Regular Article Physicochemical, functional, and evolutionary characteristics of protein loop regions in human and Escherichia coli proteomes Lin Zhang, Hafumi Nishi DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0031 Promotional Videohttps://www.youtube.com/watch?v=mpn5rNLXv2o ReceivedMay 27, 2024 AcceptedNovember 20, 2025 ReleasedNovember 22, 2025 Citations0 Downloads396 |
Regular Article Schiff base deprotonation and structural changes in a mouse UV-sensitive cone visual pigment revealed by FTIR spectroscopy at 77 K Yosuke Mizuno, Sora Arai, Kota Katayama, Hideki Kandori DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0030 Promotional Videohttps://www.youtube.com/watch?v=CUOccETkOjs ReceivedOctober 09, 2025 AcceptedNovember 15, 2025 ReleasedNovember 21, 2025 Citations0 Downloads497 |
Regular Article FTIR study of the wild-type and mutant proteins of a viral rhodopsin, OLPVR1 Mako Aoyama, Kota Katayama, Hideki Kandori DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0029 Promotional Videohttps://www.youtube.com/watch?v=fFehhed4Rqw ReceivedOctober 07, 2025 AcceptedNovember 10, 2025 ReleasedNovember 12, 2025 Citations0 Downloads527 |
Review Article (Invited) Selection–diversification interplay in oligonucleotide chemical evolution Jiro Kakizaki, Ryo Mizuuchi DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0028 Promotional Videohttps://www.youtube.com/watch?v=kUHPyXt4oUI ReceivedSeptember 16, 2025 AcceptedNovember 01, 2025 ReleasedNovember 05, 2025 Citations0 Downloads880 |
Editorial Announcement of BPPB paper awards 2025 Haruki Nakamura DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0027 ReceivedOctober 21, 2025 AcceptedOctober 21, 2025 ReleasedOctober 23, 2025 Citations0 Downloads415 |
Regular Article Fractal dimensions for tumour-related cell types of prostate cancer on histopathology images using multiple-threshold box counting algorithm Anton Schwarz, Hidetaka Arimura, Yunhao Cui, Shun Shimabukuro, Qijing Lin, Yu Jin, Satoshi Kobayashi, Takashi Matsumoto, Masaki Shiota, Masatoshi Eto, Yoshinao Oda DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0026 Promotional Videohttps://www.youtube.com/watch?v=HB9v5P9o0Aw ReceivedSeptember 04, 2025 AcceptedOctober 06, 2025 ReleasedOctober 18, 2025 Citations0 Downloads544 |
Method and Protocol (Invited) A platform for analyzing translational control by RBPs at single-mRNA resolution in cells Hotaka Kobayashi, Robert H. Singer DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0025 Promotional Videohttps://www.youtube.com/watch?v=-DKixrOMjH4 ReceivedSeptember 01, 2025 AcceptedOctober 06, 2025 ReleasedOctober 08, 2025 Citations0 Downloads805 |
Regular Article Molecular properties of a viral heliorhodopsin, V2HeR2 Ritsu Mizutori, Kota Katayama, Masae Konno, Keiichi Inoue, Oded Béjà, Hideki Kandori DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0024 Promotional Videohttps://www.youtube.com/watch?v=DxZge4fcTzo ReceivedJune 24, 2025 AcceptedOctober 02, 2025 ReleasedOctober 04, 2025 Citations0 Downloads853 |
Review Article (Invited) Stress fiber contraction induces cell body rotation in single keratocytes Chika Okimura DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0023 Promotional Videohttps://www.youtube.com/watch?v=6TSrYp8hdGM ReceivedJuly 25, 2025 AcceptedOctober 02, 2025 ReleasedOctober 04, 2025 Citations0 Downloads632 |
Regular Article Finding differentially expressed genes between cell fates predicted by image-based deep learning Tomoaki Okaniwa, Kirill Kryukov, Katsuyuki Shiroguchi DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0022 Promotional Videohttps://www.youtube.com/watch?v=obJ-tkMf4-s ReceivedMay 02, 2025 AcceptedSeptember 24, 2025 ReleasedSeptember 26, 2025 Citations0 Downloads752 |
Commentary and Perspective Interdisciplinary investigations into the biophysics of the origins of life Tony Z. Jia, Yutetsu Kuruma DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0021 ReceivedSeptember 08, 2025 AcceptedSeptember 10, 2025 ReleasedSeptember 12, 2025 Citations0 Downloads662 |
Commentary and Perspective Approaching active matter from biophysics perspective Masayuki Hayakawa, Ibuki Kawamata DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0020 ReceivedAugust 25, 2025 AcceptedAugust 29, 2025 ReleasedAugust 30, 2025 Citations0 Downloads399 |
Regular Article Visualization of peptidoglycan layer isolated from gliding diderm bacteria, Flavobacterium johnsoniae and Myxococcus xanthus, by quick-freeze deep-etch replica electron microscopy Yuhei O. Tahara, Tâm Mignot, Makoto Miyata DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0019 Promotional Videohttps://www.youtube.com/watch?v=wCfIeL-y3p4 ReceivedFebruary 06, 2025 AcceptedAugust 22, 2025 ReleasedAugust 26, 2025 Citations0 Downloads406 |
Regular Article Origin of the unique topology of the triangular water cluster in Rubrobacter xylanophilus rhodopsin Tomoyasu Noji, Msasaki Tsujimura, Keisuke Saito, Keiichi Kojima, Yuki Sudo, Hiroshi Ishikita DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0018 Promotional Videohttps://www.youtube.com/watch?v=pCxxojfEnk0 ReceivedApril 28, 2025 AcceptedAugust 21, 2025 ReleasedAugust 23, 2025 Citations1 Downloads451 |
Regular Article Polymerization and stability of actin conjugated with polyethylene glycol Masaya Sagara, Kuniyuki Hatori DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0017 Promotional Videohttps://www.youtube.com/watch?v=pR80v861L1Y ReceivedMarch 10, 2025 AcceptedAugust 06, 2025 ReleasedAugust 08, 2025 Citations0 Downloads378 |
Regular Article Characterizing deterioration of milk through bioimpedance spectroscopy Abhishek Mallick, Bishal Paul, Anirudhha Roy, Arijit Roy DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0016 Promotional Videohttps://www.youtube.com/watch?v=kBNB5lpZL_8 ReceivedApril 21, 2025 AcceptedJuly 29, 2025 ReleasedAugust 02, 2025 Citations0 Downloads395 |
Regular Article Protein–ligand affinity prediction via Jensen-Shannon divergence of molecular dynamics simulation trajectories Kodai Igarashi, Masahito Ohue DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0015 Promotional Videohttps://www.youtube.com/watch?v=l-lmHOI-kus ReceivedFebruary 20, 2025 AcceptedJuly 11, 2025 ReleasedJuly 16, 2025 Citations0 Downloads683 |
Regular Article HulaChrimson: A Chrimson-like cation channelrhodopsin discovered using freshwater metatranscriptomics from Lake Hula Hiroto Takahashi, Shunki Takaramoto, Takashi Nagata, Shai Fainsod, Yoshitaka Kato, Oded B？j？, Keiichi Inoue DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0014 Promotional Videohttps://www.youtube.com/watch?v=4rBDYxburuQ ReceivedApril 14, 2025 AcceptedJuly 03, 2025 ReleasedJuly 05, 2025 Citations1 Downloads817 |
Review Article (Invited) Cytoskeleton as a generator of characteristic physical properties of plant cells: ‘cell wall,’ ‘large vacuole,’ and ‘cytoplasmic streaming’ Amari Toshiki, Noriko Nagata, Motoki Tominaga, Hirotomo Takatsuka DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0013 Promotional Videohttps://www.youtube.com/watch?v=QnbU86t_G5k ReceivedJanuary 31, 2025 AcceptedJune 18, 2025 ReleasedJune 20, 2025 Citations0 Downloads882 |
Method and Protocol A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality Arima Okutani, Jannatul Naima, Asaka Ogihara, Taihei Motoichi, Ikuroh Ohsawa, Yoshihiro Ohta DOIhttps://doi.org/10.2142/biophysico.bppb-v22.0012 ReceivedApril 07, 2025 AcceptedMay 14, 2025 ReleasedMay 16, 2025 Citations1 Downloads701 |
