2021年03月24日 学会誌
日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。
Yasumichi Takase, Yoichi Yamazaki, Yugo Hayashi, Sachiko Toma-Fukai, Hironari Kamikubo
"Structure elements can be predicted using the contact volume among protein residues"
【Significance】
This study aims to develop a computational method that can be used to predict structure elements (SEs) of proteins instead of experimental analysis. Additionally, the building block of the protein responsible for foldability is closely related to the extent of internal molecular packing. We believe that our study makes a significant contribution to the literature because it details a contact volume profiling method that can be implemented as a time- and cost-effective alternative to comprehensive Ala-insertion mutation analysis or circular permutation analysis.
Biophysics Physicobiology, 2021, Volume 18, Pages 50-59
URL: https://doi.org/10.2142/biophysico.bppb-v18.006