「Biophysics and Physicobiology」に Yuki Kogo, Chiaki Seto, Yuki Totani, Mai Mochizuki, Taka Nakahara, Kotaro Oka, Tohru Yoshioka, Etsuro Ito による "Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K⁺ stimulation" を掲載

2020年11月06日 学会誌

日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が公開されました。

Yuki Kogo, Chiaki Seto, Yuki Totani, Mai Mochizuki, Taka Nakahara, Kotaro Oka, Tohru Yoshioka, Etsuro Ito
"Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K⁺ stimulation"

【Significance】
It is difficult to induce human dental pulp stem cells (hDPSCs) to differentiate neurons. Activation of K⁺ channels is thought to regulate the intracellular Ca²⁺ concentration, allowing for manipulation of the cell cycle to induce the differentiation of hDPSCs. Our findings indicate that cell cycle regulation by stimulation with high K⁺ accelerates the differentiation of hDPSCs into neurons.

Biophysics Physicobiology, Vol.17, pp132-139


URL: https://doi.org/10.2142/biophysico.BSJ-2020023

シェア