An article with the title "Analysis of the mechanism of synaptic integration focusing on the charge held in the spine" by Takayoshi Tsubo is published.
2021 December 18 BPPB
A following article is published in "Biophysics and Physicobiology".
Takayoshi Tsubo
"Analysis of the mechanism of synaptic integration focusing on the charge held in the spine"
【Significance】
In this study, it was clarified that high reproducibility of synaptic integration is achieved by propagating the polarization of the medium adjacent to the charge held in each spine and adding it to raise the membrane potential. Furthermore, using the approach of this study, it was possible to clarify that spine neck capacitance and spine head size contribute significantly to synaptic integration, that distant spines are able to contribute to synaptic integration, that a single neuron is able to integrate a large number of input combinations, and that inhibitory post-synapses on dendrites effectively suppress the success of synaptic integration.
Biophysics Physicobiology, 2021, Volume 18, Pages 290-304
URL:https://doi.org/10.2142/biophysico.bppb-v18.036
