「Biophysics and Physicobiology」にKazuhiro Takemura et al. “More efficient screening of protein-protein complex model structures for reducing the number of candidates”を掲載
2019 November 29 BPPB
日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が新規掲載されました。
Kazuhiro Takemura, Akio Kitao “More efficient screening of protein-protein complex model structures for reducing the number of candidates”
【Significance】
Efficient screening of docking model structure
We proposed an efficient screening method to decrease the number of protein-protein complex model structures (decoys) using a relatively simple clustering method. By applying our approach to the decoys generated by the rigid-body docking method, ZDOCK, we reduced the number of decoys by 93% compared to ZDOCK in terms of the number of decoys containing at least one near-native decoy with 90% probability. After clustering using the fraction of common contacts, the top 1,000 success rate (defined as the rate having at least one near-native model in the selected decoys) reached 97%.
Biophysics and Physicobiology, Vol.16, 295-303
URL:https://doi.org/10.2142/biophysico.16.0_295
