「Biophysics and Physicobiology」にShigeki Mitaku et al. “Biological meaning of “habitable zone” in nucleotide composition space”を掲載

2018 April 23 BPPB

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Shigeki Mitaku, Ryusuke Sawada “Biological meaning of “habitable zone” in nucleotide composition space”

Biological meaning of “habitable zone” in nucleotide composition space

We studied on the question of how genome sequences describe “life” where a large number of biomolecules are harmonized. We found that all organisms are plotted in a narrow region called habitable zone of the nucleotide composition space from the genome sequence. We discussed the biological significance of the habitable zone from three aspects: the great reduction of the number of possible sequences, the relationship between the second letter and the distribution of membrane proteins, and the relationship between the first letter and molecular recognition units. Hypotheses for the mechanism of the habitable zone formation were also discussed.

Biophysics and Physicobiology, Vol.15, pp. 75-85


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