An article with the title "Phenotypic systems biology for organisms: Concepts, methods and case studies" by Takao K. Suzuki is published.
2022 April 20 BPPB
A following article is published in "Biophysics and Physicobiology".
Takao K. Suzuki
"Phenotypic systems biology for organisms: Concepts, methods and case studies"
【Significance】
Design principles of phenotypes in organisms are fundamental issues in physical biology. In contrast to much progress in understanding the “molecular systems” of living organisms, “phenotypic systems” remains poorly understood. Here I review concepts, methods, and case studies using butterfly and moth wing patterns to explore phenotypes as systems. This review provides a unifying framework termed multi-component systems, including how to find phenotypic components (parts and interactions). In addition, evolutionary dynamics of multi-component systems are provided. Finally, I propose the next key concepts, macro-evolutionary pathways and genotype-phenotype loops. I hope these efforts will create the next generations of textbooks.
Biophysics Physicobiology, 2022, Volume 19, Article ID: e190011
URL:https://doi.org/10.2142/biophysico.bppb-v19.0011
