An article with the title "Current status of neutron crystallography in structural biology" by Fumiaki Kono, Kazuo Kurihara, Taro Tamada is published.
2022 April 16 BPPB
A following article is published in "Biophysics and Physicobiology".
Fumiaki Kono, Kazuo Kurihara, Taro Tamada
"Current status of neutron crystallography in structural biology"
【Significance】
Neutron crystallography enables direct observation of hydrogen atoms, which are crucial in the physiological functions of enzymes, including molecular recognition through hydrogen bonding and catalytic reactions. The use of neutron crystallography for protein structure determination has been limited, but its popularity is increasing along with increases in the number of diffractometers for structural biology at neutron facilities and advances in sample preparation. In this review, we describe the current status of neutron crystallography for structural biology and present our recent neutron structure analyses of copper amine oxidase and copper-containing nitrite reductase, which provide an in-depth understanding of the enzymatic catalysis.
Biophysics Physicobiology, 2022, Volume 19, Article ID: e190009
URL:https://doi.org/10.2142/biophysico.bppb-v19.0009
