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「Biophysics and Physicobiology」に Aya Okuda, Rintaro Inoue, Ken Morishima, Tomohide Saio, Yasuhiro Yunoki, Maho Yagi-Utsumi, Hirokazu Yagi, Masahiro Shimizu, Nobuhiro Sato, Reiko Urade, Koichi Kato, Masaaki Sugiyama による "Deuteration Aiming for Neutron Scattering" を掲載

2021 March 18 BPPB

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。

Aya Okuda, Rintaro Inoue, Ken Morishima, Tomohide Saio, Yasuhiro Yunoki, Maho Yagi-Utsumi, Hirokazu Yagi, Masahiro Shimizu, Nobuhiro Sato, Reiko Urade, Koichi Kato, Masaaki Sugiyama
"Deuteration Aiming for Neutron Scattering"

【Significance】
Selective studies on the target protein in the complex or the multi-component system are possible with neutron scattering assisted by deuterated protein. However, following three problems impeded the neutron scattering studies by normal users. The first one is the requirement of deuterated protein of which the deuteration level is controlled. The second one is the difficulty for efficient determination of the degree of deuteration of protein. The third one is the high cost for sample preparation. Then, we provide the protocol of protein deuteration technique, offering more opportunity for neutron scattering coupled with deuterated protein by normal users.

Biophysics Physicobiology, 2021, Volume 18, Pages 16-27



URL:https://doi.org/10.2142/biophysico.bppb-v18.003



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