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Simulation of cells lacking adaptation in higher midpoint concentration

Department of Electrical and Computer Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America Professor Pablo A. Iglesias

This simulation shows the response of the cell to a 19% gradient pointing to the right. The inhibitor level of the LEGI mechanism has been set constant, so the cell cannot adapt or adjust sensitivity. The midpoint chemoattractant concentration has been increased.

Plos Computational Biology

(2014.08.27)

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