Title
Overviewing Multilateral Approaches to Rhodopsin Systems

Organizers
Shuji Tachibanaki (Osaka University), Takahiro Yamashita (Kyouto University)

Synopsis
Rhodopsin is a photoreceptive protein of photoreceptor cells in animal eyes. Since its discovery, a lot of researches on rhodopsin molecule itself and on the rhodopsin-triggered phototransduction mechanism have been performed. Today, rhodopsin-triggerd system is one of the best understood signal-transduction systems.
In addition, rhodopsin-like proteins have been found in various species including animals, plants and bacteria, and in various tissues. It is also found that the functions of rhodopsin-like proteins are not limited to visual perception. The vast variety of rhodopsin-like proteins and their functions enables us to do comparative studies, and it brings us comprehensive understanding of molecular mechanisms in various photoreceptions.
In this symposium, we would like to overview multilateral researches in rhodopsin systems, and also discuss the possible future development of rhodopsin studies in biophysical field.

Speakers
・ Shuji Tachibanaki (Osaka University): Molecular mechanisms determining characteristics of photoresponse in rod / cone photoreceptor cells.
・ Keiji Seno (Hamamatsu University School of Medicine): Single molecule imaging of rhodopsin and transducin in native disk membrane of rod photoreceptor
・ Takahiro Yamashita (Kyoto University): Molecular mechanism regulating active state formation and G protein activation of a prototypical GPCR, vertebrate rhodopsin
・ Mikihiro Shibata (Kanazawa University): Visualization of dynamic molecular processes in photo-activated Bacteriorhodopsin by high-speed AFM
・ Hiromu Yawo (Tohoku University): New-generation channelrhodopsins: design, evaluation and application to neuroscience








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