「Biophysics and Physicobiology」に Shunpei Hanai, Kota Katayama, Hiroo Imai, Hideki Kandori による "Light-induced difference FTIR spectroscopy of primate blue-sensitive visual pigment at 163 K" を掲載
2021 March 24 BPPB
日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が公開されました。
Shunpei Hanai, Kota Katayama, Hiroo Imai, Hideki Kandori
"Light-induced difference FTIR spectroscopy of primate blue-sensitive visual pigment at 163 K"
【Significance】
Primary batho-intermediate of visual pigments exhibits photoequilibrium with the unphotolyzed state. Such photochromic property was highly advantageous for the IR study of color visual pigments at 77 K. Although it was not applicable to late intermediates, presumably because of large structural changes to proteins, we found the photochromic property between monkey blue pigment and its BL intermediate at 163 K. Detailed FTIR analysis at 77 and 163 K provided structural information on the retinal chromophore, transmembrane helices, carboxylic acids and protein-bound water molecules, which reveals how primate blue pigment changes structures for signal transduction.
Biophysics Physicobiology, 2021, Volume 18, Pages 40-49
URL:https://doi.org/10.2142/biophysico.bppb-v18.005
