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「Biophysics and Physicobiology」に Yuki Kogo, Chiaki Seto, Yuki Totani, Mai Mochizuki, Taka Nakahara, Kotaro Oka, Tohru Yoshioka, Etsuro Ito による "Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K+ stimulation" を掲載

2020 November 06 BPPB

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。

Yuki Kogo, Chiaki Seto, Yuki Totani, Mai Mochizuki, Taka Nakahara, Kotaro Oka, Tohru Yoshioka, Etsuro Ito
"Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K+ stimulation"

【Significance】
It is difficult to induce human dental pulp stem cells (hDPSCs) to differentiate neurons. Activation of K+ channels is thought to regulate the intracellular Ca2+ concentration, allowing for manipulation of the cell cycle to induce the differentiation of hDPSCs. Our findings indicate that cell cycle regulation by stimulation with high K+ accelerates the differentiation of hDPSCs into neurons.

Biophysics Physicobiology, Vol.17, pp132-139



URL:https://doi.org/10.2142/biophysico.BSJ-2020023



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