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「Biophysics and Physicobiology」に Yudai Yamaoki,Takashi Nagata,Tomoki Sakamoto,Masato Katahira による“Observation of nucleic acids inside living human cells by in-cell NMR spectroscopy”を掲載

2020年06月23日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。

Yudai Yamaoki,Takashi Nagata,Tomoki Sakamoto,Masato Katahira “Observation of nucleic acids inside living human cells by in-cell NMR spectroscopy”

【Significance】Inside a living cell, where nucleic acids exist, is highly crowded with biological macromolecules. The nucleic acids inside the cells have been thought to possess different structural features from those in vitro. To investigate those features of nucleic acids in living cells, the in-cell NMR method is a powerful tool. We have successfully expanded the in-cell NMR method for nucleic acids used for Xenopus laevis oocytes to human cells. We performed the first measurements of in-cell NMR spectra of nucleic acids forming hairpin structures in living human cells.

Biophysics and Physicobiology,Vol.17,pp.36-41
URL:https://doi.org/10.2142/biophysico.BSJ-2020006


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