ニュース

「Biophysics and Physicobiology」にKunihiko Gekko “Synchrotron-radiation vacuum-ultraviolet circular dichroism spectroscopy in structural biology: an overview”を掲載

2019年02月08日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Kunihiko Gekko “Synchrotron-radiation vacuum-ultraviolet circular dichroism spectroscopy in structural biology: an overview”

【Significance】
Synchrotron-Radiation Vacuum-Ultraviolet Circular Dichroism Spectroscopy in Structural Biology

Vacuum-ultraviolet circular dichroism (VUVCD) spectroscopy (down to ~160 nm) using synchrotron radiation provides detailed and new information unobtainable in the far-UV region down to 190 nm. This spectroscopy discloses the equilibrium conformation of saccharides and amino acids associated with hydration. VUVCD spectroscopy can markedly improve estimations of the contents and number of segments of protein secondary structures, and their amino acid sequences when combined with bioinformatics. This spectroscopy also makes more-detailed conformational analysis of nucleic acids possible through comparative studies of synthetic polynucleotides. This review surveys these recent applications of synchrotron-radiation VUVCD spectroscopy that is now becoming an important tool in structural biology.



Biophysics and Physicobiology, Vol.16, pp. 41-58
URL: https://doi.org/10.2142/biophysico.16.0_41


前のページに戻る