ニュース

「Biophysics and Physicobiology」にAkiko Higuchi et al. “iMusta4SLC: Database for the structural property and variations of solute carrier transporters”を掲載

2018年04月27日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Akiko Higuchi, Naoki Nonaka, Kei Yura “iMusta4SLC: Database for the structural property and variations of solute carrier transporters”

【Significance】
iMusta4SLC: Database for the structural property and variations of solute carrier transporters

Solute Carrier (SLC) transporter is the largest superfamily in membrane transporters. SLC transporters have a key role in nutrient intake to the cell. Previous experimental and clinical studies have reported the relationship between variants found in human SLC genes and clinical phenotypes. However the atomic mechanisms of the variation in the amino acid sequence leading to the alteration of the structure, dynamics, function and phenotype are still unknown. We therefore built iMusta4SLC that integrated the known related data to assist the simultaneous analyses of variation data and protein structural properties on SLC transporters.

Biophysics and Physicobiology, Vol.15, pp. 94-103URL:https://www.jstage.jst.go.jp/article/biophysico/15/0/15_94/_article


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